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Latex allergy. Pediatric Asthma Allergy & Immunology 13, 1-14.
| Kandeel A.A., Akl, Michel (1999).
| Allergy to natural rubber latex (NRL) is one of the major health concerns of the century. Type I anaphylactic reactions are caused by sensitivity to natural latex sap proteins remaining in latex products. Type IV contact dermatitis reactions are caused by chemical additives used to manufacture rubber products. Populations at high risk to develop latex allergy include latex industry workers, health care workers, adults and children undergoing multiple surgeries for conditions such as spina bifida, neurologic disorders, and urologic abnormalities, and atopic patients with allergy especially to avocadoes, chestnuts, bananas, and kiwi. The diagnosis of latex allergy is based on an awareness of high risk groups, a detailed history, skin prick tests or radioallergosorbent tests (RASTs) with latex reagents with high sensitivity and specificity, and patch tests to rubber accelerators and antioxidants. The mainstay of management of latex allergy is avoidance of exposure to latex. The Food and Drug Administration and The American Academy and American College of Allergy, Asthma and Immunology have made recommendations to reduce the risk of allergic reactions and occupational asthma caused by latex. This paper reviews the salient features of allergy to natural rubber latex.
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